Investigation:
1)History with suggestive pathology
- Sudden onset: Foreign body or impaction of food on a preexisting stricture or malignancy, neurological disorders.
- Progressive: Malignancy.
- Intermittent: Spasms or spasmodic episodes over an organic lesion.
- Dysphagia more to liquids seen in paralytic lesions.
- Dysphagia more to solids and progressing even to liquids seen in malignancy or strictures.
- Ulcerative lesions cause intolerance to acid food or fruit juices.
- Regurgitation and heart burn (hiatus hernia).
- Regurgitation of undigested food while lying down, with cough at night (pharyngeal pouch).
- Aspiration into lungs (laryngeal paralysis).
- Aspiration into the nose (palatal paralysis).
2) Clinical examination
Examination of oral cavity, oropharynx, larynx and hypopharynx done to exclude pre-oesophageal causes of dysphagia. Examination of the neck, chest and nervous system done.
3) Blood examination to exclude Plummer–Vinson syndrome and to know the nutritional status of the patient.
4) Radiography
- X-ray chest to exclude cardiovascular, pulmonary and mediastinal diseases.
- Lateral view neck to exclude cervical osteophytes and any soft tissue lesions of postcricoid or retropharyngeal space.
- Barium swallow to diagnose malignancy, cardiac achalasia, strictures, diverticula, hiatus hernia or oesophageal spasms.
5) Manometric and pH studies are done to help in motility disorders, gastro-oesophageal reflux and to differentiate whether oesophageal spasms are spontaneous or acid induced.
6) Oesophagoscopy for direct examination of oesophageal mucosa and if needed biopsy can be taken from the suspected oesophagus.
7)Other investigations– Bronchoscopy (for bronchial carcinoma), cardiac catheterization (for vascular anomalies), thyroid scan (for malignant thyroid) may be required, depending on the case.